{"id":15018,"date":"2025-09-18T17:49:59","date_gmt":"2025-09-18T22:49:59","guid":{"rendered":"https:\/\/www.voicesforvaccines.org\/?post_type=jtf_topics&#038;p=15018"},"modified":"2025-09-27T17:57:40","modified_gmt":"2025-09-27T22:57:40","slug":"are-there-randomized-controlled-trials-for-vaccines","status":"publish","type":"jtf_topics","link":"https:\/\/www.voicesforvaccines.org\/es\/jtf_topics\/are-there-randomized-controlled-trials-for-vaccines\/","title":{"rendered":"Are there randomized controlled trials for vaccines?"},"content":{"rendered":"<div class=\"wpb-content-wrapper\">[vc_row source=&#8221;&#8221; text=&#8221;Clinical Trials&#8221; font_container=&#8221;tag:h2|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221; google_fonts=&#8221;font_family:Abril%20Fatface%3Aregular|font_style:400%20regular%3A400%3Anormal&#8221; link=&#8221;&#8221; css=&#8221;.vc_custom_1708910874436{border-top-width: 1px !important;border-right-width: 1px !important;border-bottom-width: 1px !important;border-left-width: 1px !important;}&#8221;][vc_column][vc_row_inner][vc_column_inner][vc_custom_heading text=&#8221;The Claim:&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;][vc_column_text css=&#8221;&#8221;]In the same hearing led by Senator Ron Johnson, Dr. Jake Scott showed\u00a0<a href=\"https:\/\/docs.google.com\/spreadsheets\/u\/0\/d\/1bX4SAJwMUufNAkBplhKHOIe4gdI0BeRhpAXM5hpfV_Y\/htmlview?pli=1&amp;urp=gmail_link#gid=0\" target=\"_blank\" rel=\"noopener\">a list of RCTs<\/a>\u00a0(randomized controlled trials) for vaccination over time. Anti-vaxxers disagree with this list.\u00a0Aaron Siri claimed\u00a0that out of the 661 vaccine trials cited, none were &#8220;true&#8221; placebo-controlled trials, leaving \u201czero clean, inert placebo-controlled studies\u201d for the childhood schedule.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner][vc_custom_heading text=&#8221;The Facts:&#8221; font_container=&#8221;tag:h3|text_align:left&#8221; use_theme_fonts=&#8221;yes&#8221;][vc_column_text css=&#8221;&#8221;]The list we have linked to above is clear and available for anyone to review. Lawyer Aaron Siri is likely hoping that people believe his analysis without reviewing it.<\/p>\n<p>Saline placebo trials have been done for many vaccines, such as\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9142061\/\" target=\"_blank\" rel=\"noopener\">Rubella<\/a>,\u00a0\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3893185\/\" target=\"_blank\" rel=\"noopener\">Pneumococcal<\/a>\u00a0disease,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2233906\/\" target=\"_blank\" rel=\"noopener\">Hib<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17484215\/\" target=\"_blank\" rel=\"noopener\">HPV<\/a>,\u00a0<a href=\"https:\/\/sph.umich.edu\/polio\/\" target=\"_blank\" rel=\"noopener\">Polio<\/a>\u00a0(The Salk version),\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2554544\/pdf\/bullwho00229-0146.pdf\" target=\"_blank\" rel=\"noopener\">Measles<\/a>,\u00a0<a href=\"https:\/\/classic.clinicaltrials.gov\/ct2\/show\/NCT00707148\" target=\"_blank\" rel=\"noopener\">Tdap<\/a>, and\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8767431\/\" target=\"_blank\" rel=\"noopener\">COVID-19<\/a>.\u00a0Sometimes a new vaccine is tested against an older vaccine, or the placebo may include an ingredient like an adjuvant or buffer that is already known to be safe.<\/p>\n<p><a href=\"https:\/\/iris.who.int\/bitstream\/handle\/10665\/94056\/9789241506250_eng.pdf;jsessionid=17ED1D2E5EF6423E9EA51B97B8126F88?sequence=1\" target=\"_blank\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/voicesforvaccines.us6.list-manage.com\/track\/click?u%3De17a65409cd8f13ba7e58cc97%26id%3D943c41b3c9%26e%3Dfc0735be13&amp;source=gmail&amp;ust=1710722919327000&amp;usg=AOvVaw0AhJHWn08UCG7yz5sA1QN9\">The\u00a0World Health Organization<\/a>\u00a0has rules for when it is ethical to use placebos in vaccine trials. It is allowed when no effective vaccine exists and the new one could help the people being studied.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4157320\/\" target=\"_blank\" rel=\"noopener\">Scientists agree<\/a>\u00a0that vaccine trials may use saline placebos, but sometimes they use another vaccine instead to keep participants safe.<\/p>\n<p>Using placebos is not allowed when a safe and effective vaccine already exists in the country where a trial is planned. It would be wrong to keep that vaccine from participants if it could put their health at risk. The same is true with cancer treatment. You would not give patients nothing when a proven treatment is available. In trials, new treatments should be compared to the best current treatment, and patients should still be able to get the standard care instead of going without any treatment at all.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Randomized controlled trials with saline placebos have been done for many vaccines. Claims that there are \u201czero clean studies\u201d ignore decades of scientific evidence.<\/p>\n","protected":false},"parent":0,"template":"","jtf_topic_subjects":[189,204,196,191,198,218],"class_list":["post-15018","jtf_topics","type-jtf_topics","status-publish","hentry","jtf_topic_subjects-covid-19","jtf_topic_subjects-dtap","jtf_topic_subjects-hpv","jtf_topic_subjects-measles","jtf_topic_subjects-polio","jtf_topic_subjects-vaccine-safety","entry","no-media"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.voicesforvaccines.org\/es\/wp-json\/wp\/v2\/jtf_topics\/15018","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.voicesforvaccines.org\/es\/wp-json\/wp\/v2\/jtf_topics"}],"about":[{"href":"https:\/\/www.voicesforvaccines.org\/es\/wp-json\/wp\/v2\/types\/jtf_topics"}],"version-history":[{"count":3,"href":"https:\/\/www.voicesforvaccines.org\/es\/wp-json\/wp\/v2\/jtf_topics\/15018\/revisions"}],"predecessor-version":[{"id":15027,"href":"https:\/\/www.voicesforvaccines.org\/es\/wp-json\/wp\/v2\/jtf_topics\/15018\/revisions\/15027"}],"wp:attachment":[{"href":"https:\/\/www.voicesforvaccines.org\/es\/wp-json\/wp\/v2\/media?parent=15018"}],"wp:term":[{"taxonomy":"jtf_topic_subjects","embeddable":true,"href":"https:\/\/www.voicesforvaccines.org\/es\/wp-json\/wp\/v2\/jtf_topic_subjects?post=15018"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}