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Can vaccination be undone?

The Claim:

In an interview on the Alex Jones Show, cardiologist Peter McCullough claims to have created an mRNA off-switch that can stop vaccine mRNA from working in the body.

The Facts:

This interview is based on a paper that claims to have discovered an ‘off-switch’ for mRNA COVID-19 vaccines. In it, Dr. McCullough says that one solution to “detox” against mRNA vaccines is to introduce small interfering RNA (siRNA), similar to mRNA along with ribonuclease targeting chimeras (RIBOTACs)

McCullough has made multiple claims, including in his paper below, that lipid nanoparticles (LNPs) can cause injury and harm. Yet in his new procedure, both siRNA and RIBOTACs use lipid nanoparticles to enter the cells to target mRNA. If using lipids to allow siRNA and RIBOTACs to enter our cells is seen as safe, we can also assume the mRNA from vaccination is safe.

McCullough thinks this procedure is necessary because of worries about how mRNA vaccines spread throughout the body.

His idea about “systemic biodistribution” comes from misconstrued data. A study in rats looked at lipid nanoparticles after mRNA vaccine injections and their distribution in organs over time. The data show that most of the nanoparticles stayed where they were injected, and some went to the liver. In the ovaries, the highest amount of nanoparticles found was very, very small (only about 0.095% after 48 hours). This amount might be even smaller in human ovaries because the dose used in the COVID vaccine is much less than what they used in the rat study.

Would this off-switch work? We doubt Dr. McCullough’s science very much, and it is unnecessary because while tiny amounts of mRNA may persist in the body, the vast majority usually degrades within days.

Disclaimer: Science is always evolving and our understanding of these topics may have evolved too since this was originally posted. Be sure to check out our most recent posts and browse the latest Just the Facts Topics for the latest.

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